Yes, many people have found themselves in a situation similar to yours. I know there is little comfort in that fact.
The really difficult thing to accept when you are rejected by a spouse is that you have almost no control over their feelings, attitudes and actions. It's as though your spouse has been replaced by someone who looks like her but isn't really her. It's very difficult to process.
I think for the time being you need to accept your wife's position and stop trying to persuade her to change her mind. The more you try to hold the family together, the more likely she will dig her heels in and see you in a negative light.
Prioritise the children. Are they safe, warm and happy? Are their living arrangements and accommodation satisfactory? If all is well with the children, you probably need to start living separately from your wife. I would also urge you to seek legal advice, not because you are intending to divorce, but it's best formalise the separation. I know this is tough but you have to take action.
Assuming you can live close to your family, take the opportunity to be present in your children's lives as much as possible. I would ensure that your relationship with your wife stays respectful and cordial but do not pursue her into doing something she does not want.
Given enough time, her feelings may change for the better towards you but please don't cling to false hope. Remember, even if you wear her down and she reluctantly agrees to reunite, you haven't won anything except more misery. A spouse has to love you and want to be with you.
In writing all this, I'm assuming your wife's mental health is stable and there is no other known reason she has for behaving in this way.
I realise this is a very difficult time for you. I went through this too and I have never have experienced anything so heartbreaking, so I do understand your sadness. Repost as many times as you would like, there are many people here that can advise and support you.